Condensationtion of 3-hydroxy pyridine alkyl isocyanides and dialkyl acetylenedicarboxylate: synthesis of 4H-chromenes

Authors

  • Bita Mohtat Department of Organic Chemistry, Karaj Branch, Islamic Azad university, Karaj, Iran
  • Mahsa Mahpeyma Department of Organic Chemistry, Karaj Branch, Islamic Azad university, Karaj, Iran
Abstract:

The reactive intermediate generated by the addition of tert-butyl and 1,1,3,3-tetramethyl butyl isocyanide and cyclohexyl isocyanide to dialkyl acetylenedicarboxylate was trapped by 3-hydroxy pyridine to produce highly functionalized 4H-chromenes in fairly good  yields.

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Journal title

volume 5  issue 2

pages  24- 27

publication date 2015-12-01

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